Recent Publications

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Title: Silver nanoparticle-embedded polymersome nanocarriers for the treatment of antibiotic-resistant infections
Authors: Benjamin M. Geilich, Anne L. van de Ven, Gloria L. Singleton, Liuda J. Sepúlveda, Srinivas Sridhar, Thomas J. Webster
Journal: Nanoscale, doi: 10.1039/C4NR05823B

Polymersome GA

 

 

 

 

 

 

 

The rapidly diminishing number of effective antibiotics that can be used to treat infectious diseases and associated complications in a physician’s arsenal is having a drastic impact on human health today. This study explored the development and optimization of a polymersome nanocarrier formed from a biodegradable diblock copolymer to overcome bacterial antibiotic resistance. Here, polymersomes were synthesized containing silver nanoparticles embedded in the hydrophobic compartment, and ampicillin in the hydrophilic compartment. Results showed for the first time that these silver nanoparticle-embedded polymersomes (AgPs) inhibited the growth of Escherichia coli transformed with a gene for ampicillin resistance (bla) in a dose-dependent fashion. Free ampicillin, AgPs without ampicillin, and ampicillin polymersomes without silver nanoparticles had no effect on bacterial growth. The relationship between the silver nanoparticles and ampicillin was determined to be synergistic and produced complete growth inhibition at a silver-to-ampicillin ratio of 1 : 0.64. In this manner, this study introduces a novel nanomaterial that can effectively treat problematic, antibiotic-resistant infections in an improved capacity which should be further examined for a wide range of medical applications.

Title: Adding MgO nanoparticles to hydroxyapatite-PLLA nanocomposites for improved bone tissue engineering applications
Authors: Daniel J. Hickey, Batur Ercan, Linlin Sun, Thomas J. Webster
Journal: Acta Biomaterialia, doi: 10.1016/j.actbio.2014.12.004

Magnesium plays an important role in the body, mediating cell–extracellular matrix interactions and bone apatite structure and density. This study investigated, for the first time, the effects of adding magnesium oxide (MgO) nanoparticles to poly (l-lactic acid) (PLLA) and to hydroxyapatite (HA) nanoparticle–PLLA composites for orthopedic tissue engineering applications. Results showed that MgO nanoparticles significantly enhanced osteoblast adhesion and proliferation on HA–PLLA nanocomposites while maintaining mechanical properties (Young’s modulus ∼1000 MPa) suitable for cancellous bone applications. Additionally, osteoblasts (or bone-forming cells) cultured in the supernatant of degrading nanocomposites showed improved proliferation in the presence of magnesium, indicating that the increased alkalinity of solutions containing MgO nanocomposites had no toxic effects towards cells. These results together indicated the promise of further studying MgO nanoparticles as additive materials to polymers to enhance the integration of implanted biomaterials with bone.

2017

[1]      O. Gokcekaya, T. J. Webster, K. Ueda, T. Narushima, and C. Ergun, “In vitro performance of Ag-incorporated hydroxyapatite and its adhesive porous coatings deposited by electrostatic spraying,” Mater. Sci. Eng. C, vol. 77, pp. 556–564, 2017.

[2]      J. Zhang, L. Sun, P. A. Zapata, M. Arias, L. Atehortuac, and T. J. Webster, “Anti-Inflammatory Bone Protective Effects of Nano-Protein Extracts from Mushroom Species: Ganoderma lucidum and Pleurotus ostreatus,” J. Nanosci. Nanotechnol., vol. 17, no. 8, pp. 5884–5889, 2017.

[3]      Y. Li, Y. Zhang, P. Li, G. Mi, J. Tu, L. Sun, T. J. Webster, and Y. Shen, “Ion-paired pirenzepine-loaded micelles as an ophthalmic delivery system for the treatment of myopia,” Nanomedicine Nanotechnology, Biol. Med., 2017.

[4]      J. Zhang, M. Wang, and T. J. Webster, “Growth Process and Anti-Cancer Properties of Gold Nanorods,” J. Biomed. Mater. Res. Part A, May 2017.

[5]      M. M. Alvarez, J. Aizenberg, M. Analoui, A. M. Andrews, G. Bisker, E. S. Boyden, R. D. Kamm, J. M. Karp, D. J. Mooney, R. Oklu, D. Peer, M. Stolzoff, M. S. Strano, G. Trujillo-de Santiago, T. J. Webster, P. S. Weiss, and A. Khademhosseini, “Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation,” ACS Nano, p. acsnano.7b01493, May 2017.

[6]      A. Hussain, S. Singh, T. J. Webster, and F. J. Ahmad, “New perspectives in the topical delivery of optimized amphotericin B loaded nanoemulsions using excipients with innate anti-fungal activities: A mechanistic and histopathological investigation,” Nanomedicine Nanotechnology, Biol. Med., vol. 13, no. 3, pp. 1117–1126, 2017.

[7]      G. F. Santana-Melo, B. V. M. Rodrigues, E. da Silva, R. Ricci, F. R. Marciano, T. J. Webster, L. M. R. Vasconcellos, and A. O. Lobo, “Electrospun ultrathin PBAT/nHAp fibers influenced the in vitro and in vivo osteogenesis and improved the mechanical properties of neoformed bone,” Colloids Surfaces B Biointerfaces, vol. 155, pp. 544–552, 2017.

[8]      E. Silva, L. M. R. de Vasconcellos, B. V. M. Rodrigues, D. M. dos Santos, S. P. Campana-Filho, F. R. Marciano, T. J. Webster, and A. O. Lobo, “PDLLA honeycomb-like scaffolds with a high loading of superhydrophilic graphene/multi-walled carbon nanotubes promote osteoblast in vitro functions and guided in vivo bone regeneration,” Mater. Sci. Eng. C, vol. 73, pp. 31–39, 2017.

[9]      B. M. Geilich, I. Gelfat, S. Sridhar, A. L. van de Ven, and T. J. Webster, “Superparamagnetic iron oxide-encapsulating polymersome nanocarriers for biofilm eradication,” Biomaterials, vol. 119, pp. 78–85, 2017.

[10]    T. V. Toniatto, B. V. M. Rodrigues, T. C. O. Marsi, R. Ricci, F. R. Marciano, T. J. Webster, and A. O. Lobo, “Nanostructured poly (lactic acid) electrospun fiber with high loadings of TiO2 nanoparticles: Insights into bactericidal activity and cell viability,” 2017.

[11]    L. P. Gabriel, M. E. M. dos Santos, A. L. Jardini, G. N. T. Bastos, C. G. B. T. Dias, T. J. Webster, and R. Maciel Filho, “Bio-based polyurethane for tissue engineering applications: How hydroxyapatite nanoparticles influence the structure, thermal and biological behavior of polyurethane composites,” Nanomedicine Nanotechnology, Biol. Med., vol. 13, no. 1, pp. 201–208, 2017.

[12]    X. Lin, S. Yang, K. Lai, H. Yang, T. J. Webster, and L. Yang, “Orthopedic implant biomaterials with both osteogenic and anti-infection capacities and associated in vivo evaluation methods,” Nanomedicine Nanotechnology, Biol. Med., vol. 13, no. 1, pp. 123–142, 2017.

[13]    D. Kumari, L. Sheikh, S. Bhattacharya, T. J. Webster, and S. Nayar, “Two-dimensional collagen-graphene as colloidal templates for biocompatible inorganic nanomaterial synthesis.,” Int. J. Nanomedicine, vol. 12, pp. 3605–3616, 2017.

[14]    C. Bartomeu Garcia, D. Shi, and T. J. Webster, “Tat-functionalized liposomes for the treatment of meningitis: an in vitro study.,” Int. J. Nanomedicine, vol. 12, pp. 3009–3021, 2017.

[15]    H. Jahangirian, E. G. Lemraski, T. J. Webster, R. Rafiee-Moghaddam, and Y. Abdollahi, “A review of drug delivery systems based on nanotechnology and green chemistry: green nanomedicine.,” Int. J. Nanomedicine, vol. 12, pp. 2957–2978, 2017.

[16]    G. Mi, D. Shi, W. Herchek, and T. J. Webster, “Self-assembled arginine-rich peptides as effective antimicrobial agents,” J. Biomed. Mater. Res. Part A, vol. 105, no. 4, pp. 1046–1054, Apr. 2017.

[17]    J. Penders, M. Stolzoff, D. J. Hickey, M. Andersson, and T. J. Webster, “Shape-dependent antibacterial effects of non-cytotoxic gold nanoparticles.,” Int. J. Nanomedicine, vol. 12, pp. 2457–2468, 2017.

[18]    E. Alpaslan, B. M. Geilich, H. Yazici, and T. J. Webster, “pH-Controlled Cerium Oxide Nanoparticle Inhibition of Both Gram-Positive and Gram-Negative Bacteria Growth.,” Sci. Rep., vol. 7, p. 45859, Apr. 2017.

[19]    F. Chai, L. Sun, X. He, J. Li, Y. Liu, F. Xiong, L. Ge, T. J. Webster, and C. Zheng, “Doxorubicin-loaded poly (lactic-co-glycolic acid) nanoparticles coated with chitosan/alginate by layer by layer technology for antitumor applications.,” Int. J. Nanomedicine, vol. 12, pp. 1791–1802, 2017.

[20]    A. J. Hassiba, M. E. El Zowalaty, T. J. Webster, A. M. Abdullah, G. K. Nasrallah, K. A. Khalil, A. S. Luyt, and A. A. Elzatahry, “Synthesis, characterization, and antimicrobial properties of novel double layer nanocomposite electrospun fibers for wound dressing applications.,” Int. J. Nanomedicine, vol. 12, pp. 2205–2213, 2017.

[21]    M. C. Machado and T. J. Webster, “Lipase degradation of plasticized polyvinyl chloride endotracheal tube surfaces to create nanoscale features.,” Int. J. Nanomedicine, vol. 12, pp. 2109–2115, 2017.

[22]    M. Stolzoff, J. E. Burns, A. Aslani, E. J. Tobin, C. Nguyen, N. De La Torre, N. H. Golshan, K. S. Ziemer, and T. J. Webster, “Decreased bacterial growth on titanium nanoscale topographies created by ion beam assisted evaporation.,” Int. J. Nanomedicine, vol. 12, pp. 1161–1169, 2017.

[23]    G. Bhardwaj and T. J. Webster, “Reduced bacterial growth and increased osteoblast proliferation on titanium with a nanophase TiO2 surface treatment.,” Int. J. Nanomedicine, vol. 12, pp. 363–369, 2017.

[24]    L. Sun, C. Zheng, and T. J. Webster, “Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls.,” Int. J. Nanomedicine, vol. 12, pp. 73–86, 2017.

[25]    J. Barlow, K. Gozzi, C. P. Kelley, B. M. Geilich, T. J. Webster, Y. Chai, S. Sridhar, and A. L. van de Ven, “High throughput microencapsulation of Bacillus subtilis in semi-permeable biodegradable polymersomes for selenium remediation,” Appl. Microbiol. Biotechnol., vol. 101, no. 1, pp. 455–464, Jan. 2017.

 

2016

Atefyekta, S., Ercan, B., Karlsson, J., Taylor, E., Chung, S., Webster, T. J., & Andersson, M. (2016). Antimicrobial performance of mesoporous titania thin films: role of pore size, hydrophobicity, and antibiotic release. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 977–990. http://doi.org/10.2147/IJN.S95375

Bhardwaj, G., & Webster, T. J. (2016). XanoMatrix surfaces as scaffolds for mesenchymal stem cell culture and growth. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 2655–2661. http://doi.org/10.2147/IJN.S101838

Bhardwaj, G., & Webster, T. J. (2016). Enhanced chondrocyte culture and growth on biologically inspired nanofibrous cell culture dishes. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 479–483. http://doi.org/10.2147/IJN.S94000

Chai, F., Sun, L., Ding, Y., Liu, X., Zhang, Y., Webster, T. J., & Zheng, C. (2016). A solid self-nanoemulsifying system of the BCS class IIb drug dabigatran etexilate to improve oral bioavailability. NANOMEDICINE, 11(14), 1801–1816. http://doi.org/10.2217/nnm-2016-0138

Cheng, M. J., Kumar, R., Sridhar, S., Webster, T. J., & Ebong, E. E. (2016). Endothelial glycocalyx conditions influence nanoparticle uptake for passive targeting. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 3305–3315. http://doi.org/10.2147/IJN.S106299

Chung, S., Ercan, B., Roy, A. K., & Webster, T. J. (2016). Addition of Selenium Nanoparticles to Electrospun Silk Scaffold Improves the Mammalian Cell Activity While Reducing Bacterial Growth. FRONTIERS IN PHYSIOLOGY, 7. http://doi.org/10.3389/fphys.2016.00297

Favi, P. M., Ospina, S. P., Kachole, M., Gao, M., Atehortua, L., & Webster, T. J. (2016). Preparation and characterization of biodegradable nano hydroxyapatite-bacterial cellulose composites with well-defined honeycomb pore arrays for bone tissue engineering applications. CELLULOSE, 23(2), 1263–1282. http://doi.org/10.1007/s10570-016-0867-4

Firouzamandi, M., Moeini, H., Hosseini, S. D., Bejo, M. H., Omar, A. R., Mehrbod, P., … Ideris, A. (2016). Preparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 259–267. http://doi.org/10.2147/IJN.S92225

Hassiba, A. J., El Zowalaty, M. E., Nasrallah, G. K., Webster, T. J., Luyt, A. S., Abdullah, A. M., & Elzatahry, A. A. (2016). Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing. NANOMEDICINE, 11(6), 715–737. http://doi.org/10.2217/nnm.15.211

Johnston, J., Taylor, E. N., Gilbert, R. J., & Webster, T. J. (2016). Improved molecular fingerprint analysis employing multi-branched gold nanoparticles in conjunction with surface-enhanced Raman scattering. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 45–53. http://doi.org/10.2147/IJN.S93222

Kotla, N. G., Singh, S., Maddiboyina, B., Sunnapu, O., & Webster, T. J. (2016). A novel dissolution media for testing drug release from a nanostructured polysaccharide-based colon specific drug delivery system: an approach to alternative colon media. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 1089–1095. http://doi.org/10.2147/IJN.S97177

Liu, L., Ercan, B., Sun, L., Ziemer, K. S., & Webster, T. J. (2016). Understanding the Role of Polymer Surface Nanoscale Topography on Inhibiting Bacteria Adhesion and Growth. ACS BIOMATERIALS-SCIENCE & ENGINEERING, 2(1), 122–130. http://doi.org/10.1021/acsbiomaterials.5b00431

Ni, S., Li, X., Yang, P., Ni, S., Hong, F., & Webster, T. J. (2016). Enhanced apatite-forming ability and antibacterial activity of porous anodic alumina embedded with CaO-SiO2-Ag2O bioactive materials. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 58, 700–708. http://doi.org/10.1016/j.msec.2015.09.011

Saifullah, B., El Zowalaty, M. E., Arulselvan, P., Fakurazi, S., Webster, T. J., Geilich, B. M., & Hussein, M. Z. (2016). Synthesis, characterization, and efficacy of antituberculosis isoniazid zinc aluminum-layered double hydroxide based nanocomposites. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 3225–3237. http://doi.org/10.2147/IJN.S102406

Singh, S., Vardhan, H., Kotla, N. G., Maddiboyina, B., Sharma, D., & Webster, T. J. (2016). The role of surfactants in the formulation of elastic liposomal gels containing a synthetic opioid analgesic. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 1475–1482. http://doi.org/10.2147/IJN.S100253

Stolzoff, M., & Webster, T. J. (2016). Reducing bone cancer cell functions using selenium nanocomposites. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 104(2), 476–482. http://doi.org/10.1002/jbm.a.35583

Yuan, B., Webster, T. J., & Roy, A. K. (2016). Cytoprotective effects of cerium and selenium nanoparticles on heat-shocked human dermal fibroblasts: an in vitro evaluation. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 1427–1433. http://doi.org/10.2147/IJN.S104082

2015

Al-Fahdawi, M. Q., Rasedee, A., Al-Qubaisi, M. S., Alhassan, F. H., Rosli, R., El Zowalaty, M. E., … Taufiq-Yap, Y. H. (2015). Cytotoxicity and physicochemical characterization of iron-manganese-doped sulfated zirconia nanoparticles. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 5739–5750. http://doi.org/10.2147/IJN.S82586

Alpaslan, E., Yazici, H., Golshan, N. H., Ziemer, K. S., & Webster, T. J. (2015). pH-Dependent Activity of Dextran-Coated Cerium Oxide Nanoparticles on Prohibiting Osteosarcoma Cell Proliferation. ACS BIOMATERIALS-SCIENCE & ENGINEERING, 1(11), 1096–1103. http://doi.org/10.1021/acsbiomaterials.5b00194

Aninwene II, G. E., Abadian, P. N., Ravi, V., Taylor, E. N., Hall, D. M., Mei, A., … Webster, T. J. (2015). Lubricin: A novel means to decrease bacterial adhesion and proliferation. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 103(2), 451–462. http://doi.org/10.1002/jbm.a.35195

Asiri, A. M., Marwani, H. M., Khan, S. B., & Webster, T. J. (2015). Understanding greater cardiomyocyte functions on aligned compared to random carbon nanofibers in PLGA. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 89–96. http://doi.org/10.2147/IJN.S74173

Bagherifard, S., Hickey, D. J., de Luca, A. C., Malheiro, V. N., Markaki, A. E., Guagliano, M., & Webster, T. J. (2015). The influence of nanostructured features on bacterial adhesion and bone cell functions on severely shot peened 316L stainless steel. BIOMATERIALS, 73, 185–197. http://doi.org/10.1016/j.biomaterials.2015.09.019

Balasundaram, G., Storey, D. M., & Webster, T. J. (2015). Molecular plasma deposition: biologically inspired nanohydroxyapatite coatings on anodized nanotubular titanium for improving osteoblast density. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 527–535. http://doi.org/10.2147/IJN.S65308

Bhardwaj, G., Yazici, H., & Webster, T. J. (2015). Reducing bacteria and macrophage density on nanophase hydroxyapatite coated onto titanium surfaces without releasing pharmaceutical agents. NANOSCALE, 7(18), 8416–8427. http://doi.org/10.1039/c5nr00471c

Chang, R., Sun, L., & Webster, T. J. (2015). Selective inhibition of MG-63 osteosarcoma cell proliferation induced by curcumin-loaded self-assembled arginine-rich-RGD nanospheres. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 3351–3365. http://doi.org/10.2147/IJN.S78756

Cheng, M. J., Kumar, R., Sridhar, S., Webster, T. J., & Ebong, E. E. (2015). Glycocalyx Integrity Influences Nanoparticle Uptake by Endothelial Cells. TISSUE ENGINEERING PART A, 21(1), S401.

El Zowalaty, M. E., Al Thani, A. A., Webster, T. J., El Zowalaty, A. E., Schweizer, H. P., Nasrallah, G. K., … Ashour, H. M. (2015). Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies. FUTURE MICROBIOLOGY, 10(10), 1683–1706. http://doi.org/10.2217/fmb.15.48

El Zowalaty, M. E., Al Ali, S. H. H., Husseiny, M. I., Geilich, B. M., Webster, T. J., & Hussein, M. Z. (2015). The ability of streptomycin-loaded chitosan-coated magnetic nanocomposites to possess antimicrobial and antituberculosis activities. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 3269–3273. http://doi.org/10.2147/IJN.S74469

Favi, P., Alvarez, S. P., Gao, M., Roy, A., & Webster, T. J. (2015). Natural Nanostructured Materials for Tissue Engineering Applications. TISSUE ENGINEERING PART A, 21(1), S200.

Favi, P. M., Gao, M., Arango, L. J. S., Ospina, S. P., Morales, M., Pavon, J. J., & Webster, T. J. (2015). Shape and surface effects on the cytotoxicity of nanoparticles: Gold nanospheres versus gold nanostars. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 103(11), 3449–3462. http://doi.org/10.1002/jbm.a.35491

Favi, P. M., Morales Valencia, M., Elliott, P. R., Restrepo, A., Gao, M., Huang, H., … Webster, T. J. (2015). Shape and surface chemistry effects on the cytotoxicity and cellular uptake of metallic nanorods and nanospheres. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 103(12), 3940–3955. http://doi.org/10.1002/jbm.a.35518

Geilich, B. M., van de Ven, A. L., Sridhar, S., & Webster, T. J. (2015). Silver Nanoparticle-Embedded Polymersome Nanocarriers for the Treatment of Antibiotic-Resistant Infections. TISSUE ENGINEERING PART A, 21(1), S358.

Guisbiers, G., Wang, Q., Khachatryan, E., Arellano-Jimenez, M. J., Webster, T. J., Larese-Casanova, P., & Nash, K. L. (2015). Anti-bacterial selenium nanoparticles produced by UV/VIS/NIR pulsed nanosecond laser ablation in liquids. LASER PHYSICS LETTERS, 12(1). http://doi.org/10.1088/1612-2011/12/1/016003

Gupta, A., Singh, S., Kotla, N. G., & Webster, T. J. (2015). Formulation and evaluation of a topical niosomal gel containing a combination of benzoyl peroxide and tretinoin for antiacne activity. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 171–182. http://doi.org/10.2147/IJN.S70449

Hickey, D. J., & Webster, T. J. (2015). Antibacterial MgO Nanomaterials for Improved Orthopedic Tissue Engineering Applications. TISSUE ENGINEERING PART A, 21(1), S159.

Hickey, D. J., Ercan, B., Sun, L., & Webster, T. J. (2015). Adding MgO nanoparticles to hydroxyapatite-PLLA nanocomposites for improved bone tissue engineering applications. ACTA BIOMATERIALIA, 14, 175–184. http://doi.org/10.1016/j.actbio.2014.12.004

Jain, A., Jain, A., Garg, N. K., Tyagi, R. K., Singh, B., Katare, O. P., … Soni, V. (2015). Surface engineered polymeric nanocarriers mediate the delivery of transferrin-methotrexate conjugates for an improved understanding of brain cancer. ACTA BIOMATERIALIA, 24, 140–151. http://doi.org/10.1016/j.actbio.2015.06.027

Karahaliloglu, Z., Ercan, B., Denkbas, E. B., & Webster, T. J. (2015). Nanofeatured silk fibroin membranes for dermal wound healing applications. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 103(1), 135–144. http://doi.org/10.1002/jbm.a.35161

Karahaliloglu, Z., Ercan, B., Taylor, E. N., Chung, S., Denkbas, E. B., & Webster, T. J. (2015). Antibacterial Nanostructured Polyhydroxybutyrate Membranes for Guided Bone Regeneration. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 11(12), 2253–2263. http://doi.org/10.1166/jbn.2015.2106

Lee, Y. K., Choi, E.-J., Webster, T. J., Kim, S.-H., & Khang, D. (2015). Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 97–112. http://doi.org/10.2147/IJN.S72998

Liu, W., Su, P., Chen, S., Wang, N., Wang, J., Liu, Y., … Webster, T. J. (2015). Antibacterial and osteogenic stem cell differentiation properties of photoinduced TiO2 nanoparticle-decorated TiO2 nanotubes (vol 10, pg 713, 2015). NANOMEDICINE, 10(9), 1536.

Liu, W., Su, P., Chen, S., Wang, N., Wang, J., Liu, Y., … Webster, T. J. (2015). Antibacterial and osteogenic stem cell differentiation properties of photoinduced TiO2 nanoparticle-decorated TiO2 nanotubes. NANOMEDICINE, 10(5), 713–723. http://doi.org/10.2217/NNM.14.183

Liu, W., Su, P., Gonzales III, A., Chen, S., Wang, N., Wang, J., … Webster, T. J. (2015). Optimizing stem cell functions and antibacterial properties of TiO2 nanotubes incorporated with ZnO nanoparticles: experiments and modeling. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 1997–2019. http://doi.org/10.2147/IJN.S74418

Lu, J., & Webster, T. J. (2015). Reduced immune cell responses on nano and submicron rough titanium. ACTA BIOMATERIALIA, 16, 223–231. http://doi.org/10.1016/j.actbio.2015.01.036

Mftah, A., Alhassan, F. H., Al-Qubaisi, M. S., El Zowalaty, M. E., Webster, T. J., Sh-eldin, M., … Rashid, S. S. (2015). Physicochemical properties, cytotoxicity, and antimicrobial activity of sulphated zirconia nanoparticles. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 765–774. http://doi.org/10.2147/IJN.S66058

Mi, G., Sun, L., Alsbaiee, A., Hemraz, U. D., Cho, J., Fenniri, H., & Webster, T. J. (2015). Functionalized Rosette Nanotubes as a Bone Regenerative and Anti-microbial Agent. TISSUE ENGINEERING PART A, 21(1), S306.

Mi, G., & Webster, T. J. (2015). Peptide Amphiphiles as an Anti-aging and Anti-wrinkle Agent. TISSUE ENGINEERING PART A, 21(1), S147.

Singh, S., Kotla, N. G., Tomar, S., Maddiboyina, B., Webster, T. J., Sharma, D., & Sunnapu, O. (2015). A nanomedicine-promising approach to provide an appropriate colon-targeted drug delivery system for 5-fluorouracil. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 7175–7182. http://doi.org/10.2147/IJN.S89030

Stolzoff, M., Burns, J. E., Aslani, A., Tobin, E. J., & Webster, T. J. (2015). Implementation of Nanorough Surface Treatments to Improve Bone-Anchored Hearing Aid Integration. TISSUE ENGINEERING PART A, 21(1), S377–S378.

Verissimo, N. C., Geilich, B. M., Oliveira, H. G., Caram, R., & Webster, T. J. (2015). Reducing Staphylococcus aureus growth on Ti alloy nanostructured surfaces through the addition of Sn. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 103(12), 3757–3763. http://doi.org/10.1002/jbm.a.35517

Wang, M., Favi, P., Keidar, M., & Webster, T. J. (2015). Cold Atmospheric Plasma (CAP) Modified 3D Printed Scaffolds for Human Mesenchymal Stem Cell (hMSC) Differentiation. TISSUE ENGINEERING PART A, 21(1), S340.

Wang, Q., Larese-Casanova, P., & Webster, T. J. (2015). Inhibition of various gram-positive and gram-negative bacteria growth on selenium nanoparticle coated paper towels. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 2885–2894. http://doi.org/10.2147/IJN.S78466

Wang, Q., & Webster, T. J. (2015). NANOCERAMICS PROCESSING: REVOLUTIONIZING MEDICINE. In Ohji, T and Singh, M and Mathur, S (Ed.), ADVANCED PROCESSING AND MANUFACTURING TECHNOLOGIES FOR NANOSTRUCTURED AND MULTIFUNCTIONAL MATERIALS (pp. 213–218).

Webster, T. J. (2015). MALAYSIAN ECONOMIC DEVELOPMENT, LEADING INDUSTRIES AND INDUSTRIAL CLUSTERS. SINGAPORE ECONOMIC REVIEW, 59(5). http://doi.org/10.1142/S0217590814500441

Webster, T. J., Lee, S., & An, S. S. A. (2015). Today’s diverse nano-theranostic applications and tomorrow’s promises. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10(SI), 1–2. http://doi.org/10.2147/IJN.S93426

Yazici, H., Alpaslan, E., & Webster, T. J. (2015). The Role of Dextran Coatings on the Cytotoxicity Properties of Ceria Nanoparticles Toward Bone Cancer Cells. JOM, 67(4), 804–810. http://doi.org/10.1007/s11837-015-1336-5

2014

Aninwene, George Ejiofor, II, Yang, Zifan, Ravi, Vishnu, Jay, Gregory D., & Webster, Thomas J. (2014). Lubricin as a novel nanostructured protein coating to reduce fibroblast density. International Journal of Nanomedicine, 9, 3131-3135. doi: 10.2147/ijn.s56439

Asiri, A. M., Marwani, H. M., Khan, S. B., & Webster, T. J. (2014). Greater cardiomyocyte density on aligned compared with random carbon nanofibers in polymer composites. International Journal of Nanomedicine, 9. doi: 10.2147/Ijn.S71587

Balasundaram, Ganesan, Storey, Daniel M., & Webster, Thomas J. (2014). Novel nano-rough polymers for cartilage tissue engineering. International Journal of Nanomedicine, 9, 1845-1853. doi: 10.2147/ijn.s55865

Bhattacharya, Soumya, Dhar, Purbarun, Das, Sarit K., Ganguly, Ranjan, Webster, Thomas J., & Nayar, Suprabha. (2014). Colloidal graphite/graphene nanostructures using collagen showing enhanced thermal conductivity. International Journal of Nanomedicine, 9, 1287-1298. doi: 10.2147/ijn.s57122

Calvert, Kayla L., Desai, Tejal, & Webster, Thomas J. (2014). Advances in calcium phosphate coatings – anodic spark deposition: a review. Frontiers in Bioscience-Landmark, 19, 475-489. doi: 10.2741/4219

Chang, Run, Sun, Linlin, & Webster, Thomas J. (2014). Short communication: selective cytotoxicity of curcumin on osteosarcoma cells compared to healthy osteoblasts. International Journal of Nanomedicine, 9, 461-465. doi: 10.2147/ijn.s55505

Hussein-Al-Ali, Amer Hasan, El Zowalaty, Mohamed Ezzat, Hussein, Mohd Zobir, Ismail, Maznah, & Webster, Thomas J. (2014). Synthesis, characterization, controlled release, and antibacterial studies of a novel streptomycin chitosan magnetic nanoantibiotic. International Journal of Nanomedicine, 9, 549-557. doi: 10.2147/ijn.s53079

Hussein-Al-Ali, Samer Hasan, El Zowalaty, Mohamed Ezzat, Hussein, Mohd Zobir, Geilich, Benjamin M., & Webster, Thomas J. (2014). Synthesis, characterization, and antimicrobial activity of an ampicillin-conjugated magnetic nanoantibiotic for medical applications. International Journal of Nanomedicine, 9, 3801-3814. doi: 10.2147/ijn.s61143

Hussein-Al-Ali, Samer Hasan, El Zowalaty, Mohamed Ezzat, Hussein, Mohd Zobir, Ismail, Maznah, Dorniani, Dena, & Webster, Thomas J. (2014). Novel kojic acid-polymer-based magnetic nanocomposites for medical applications. International Journal of Nanomedicine, 9, 351-362. doi: 10.2147/ijn.s53847

Hussein-Al-Ali, Samer Hasan, El Zowalaty, Mohamed E., Kura, Aminu Umar, Geilich, Benjamin, Fakurazi, Sharida, Webster, Thomas J., . . . Hussein, Mohd Zobir. (2014). Antimicrobial and Controlled Release Studies of a Novel Nystatin Conjugated Iron Oxide Nanocomposite. Biomed Research International. doi: 10.1155/2014/651831

Karahaliloglu, Z., Ercan, B., Chung, S., Taylor, E., Denkbas, E. B., & Webster, T. J. (2014). Nanostructured anti-bacterial poly-lactic-co-glycolic acid films for skin tissue engineering applications. Journal of Biomedical Materials Research Part A, 102(12), 4598-4608. doi: 10.1002/Jbm.A.35141

Li, Xiaohong, Ni, Siyu, & Webster, Thomas J. (2014). In vitro apatite formation on porous anodic alumina induced by a phosphorylation treatment. Journal of Biomaterials Applications, 29(3), 321-328. doi: 10.1177/0885328214526765

Lee, Y. K., Choi, E. J., Webster, T. J., Kim, S.H. Khang D. Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity. International Journal of Nanomedicine, 10, 97-113. doi: 10.2147/IJN.S72998

Liu, Wenwen, Su, Penglei, Chen, Su, Wang, Na, Ma, Yuanping, Liu, Yiran, . . . Webster, Thomas J. (2014). Synthesis of TiO2 nanotubes with ZnO nanoparticles to achieve antibacterial properties and stem cell compatibility. Nanoscale, 6(15), 9050-9062. doi: 10.1039/c4nr01531b

MacMillan, A. K., Lamberti, F. V., Moulton, J. N., Geilich, B. M., & Webster, T. J. (2014). Similar healthy osteoclast and osteoblast activity on nanocrystalline hydroxyapatite and nanoparticles of tri-calcium phosphate compared to natural bone. International Journal of Nanomedicine, 9, 5627-5637. doi: 10.2147/Ijn.S66852

Maschhoff, Paul M., Geilich, Benjamin M., & Webster, Thomas J. (2014). Greater fibroblast proliferation on an ultrasonicated ZnO/PVC nanocomposite material. International Journal of Nanomedicine, 9, 257-263. doi: 10.2147/ijn.s54897

Mathew, Dennis, Bhardwaj, Garima, Wang, Qi, Sun, Linlin, Ercan, Batur, Geetha, Manisavagam, & Webster, Thomas J. (2014). Decreased Staphylococcus aureus and increased osteoblast density on nanostructured electrophoretic-deposited hydroxyapatite on titanium without the use of pharmaceuticals. International Journal of Nanomedicine, 9, 1775-1781. doi: 10.2147/ijn.s55733

Ni, Siyu, Li, Changyan, Ni, Shirong, Chen, Ting, & Webster, Thomas J. (2014). Understanding improved osteoblast behavior on select nanoporous anodic alumina. International Journal of Nanomedicine, 9, 3325-3334. doi: 10.2147/ijn.s60346

Ni, Siyu, Sun, Linlin, Ercan, Batur, Liu, Luting, Ziemer, Katherine, & Webster, Thomas J. (2014). A mechanism for the enhanced attachment and proliferation of fibroblasts on anodized 316L stainless steel with nano-pit arrays. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 102(6), 1297-1303. doi: 10.1002/jbm.b.33127

Saifullah, B., Arulselvan, P., El, M. E., Fakurazi, H., Webster, T. J., Geilich, B. M., & Hussein, M. Z. (2014). Development of a biocompatible nanodelivery system for tuberculosis drugs based on isoniazid-Mg/Al layered double hydroxide. International Journal of Nanomedicine, 9, 4749-4762. doi: 10.2147/Ijn.S63608

Saifullah, B., Arulselvan, P., El Zowalaty, M. E., Fakurazi, S., Webster, T. J., Geilich, B., & Hussein, M. Z. (2014). Development of a Highly Biocompatible Antituberculosis Nanodelivery Formulation Based on Para-Aminosalicylic Acid-Zinc Layered Hydroxide Nanocomposites. Scientific World Journal. doi: 10.1155/2014/401460

Saifullah, Bullo, El Zowalaty, Mohamed E., Arulselvan, Palanisamy, Fakurazi, Sharida, Webster, Thomas J., Geilich, Benjamin M., & Hussein, Mohd Zobir. (2014). Antimycobacterial, antimicrobial, and biocompatibility properties of para-aminosalicylic acid with zinc layered hydroxide and Zn/Al layered double hydroxide nanocomposites. Drug Design Development and Therapy, 8, 1029-1036. doi: 10.2147/dddt.s63753

Shi, Di, Sun, Linlin, Mi, Gujie, Sheikh, Lubna, Bhattacharya, Soumya, Nayar, Suprabha, & Webster, Thomas J. (2014). Controlling ferrofluid permeability across the blood-brain barrier model. Nanotechnology, 25(7). doi: 10.1088/0957-4484/25/7/075101

Stout, D. A., Raimondo, E., Marostica, G., & Webster, T. J. (2014). Growth characteristics of different heart cells on novel nanopatch substrate during electrical stimulation. Bio-Medical Materials and Engineering, 24(6), 2101-2107. doi: 10.3233/Bme-141020

Sun, Linlin, Li, Dongni, Hemraz, Usha D., Fenniri, Hicham, & Webster, Thomas J. (2014). Self-assembled rosette nanotubes and poly(2-hydroxyethyl methacrylate) hydrogels promote skin cell functions. Journal of Biomedical Materials Research Part A, 102(10), 3446-3451. doi: 10.1002/jbm.a.35008

Taylor, Erik N., Kummer, Kim M., Dyondi, Deepti, Webster, Thomas J., & Banerjee, Rinti. (2014). Multi-scale strategy to eradicate Pseudomonas aeruginosa on surfaces using solid lipid nanoparticles loaded with free fatty acids. Nanoscale, 6(2), 825-832. doi: 10.1039/c3nr04270g

Webster, T. J., Patel, A. A., Rahaman, M. N., & Bal, B. Sonny. (2014). Anti-infective and osteointegration properties of silicon nitride, poly-ether-ether-ketone, and titanium implants (vol 8, pg 4447, 2012). Acta Biomaterialia, 10(3), 1485-1486. doi: 10.1016/j.actbio.2013.11.018

Yang, L., & Webster, T. J. (2014). Small and Bright. Ieee Pulse, 5(2), 34-39. doi: 10.1109/Mpul.2013.2296800

Yao, Chang, Webster, Thomas J., & Hedrick, Matthew. (2014). Decreased bacteria density on nanostructured polyurethane. Journal of Biomedical Materials Research Part A, 102(6), 1823-1828. doi: 10.1002/jbm.a.34856

2013

Al-Qubaisi, Mothanna Sadiq, Rasedee, Abdullah, Flaifel, Moayad Husein, Ahmad, Sahrim Hj, Hussein-Al-Ali, Samer, Hussein, Mohd Zobir, . . . El Zowalaty, Mohamed Ezzat. (2013). Induction of apoptosis in cancer cells by NiZn ferrite nanoparticles through mitochondrial cytochrome C release. International Journal of Nanomedicine, 8, 4115-4130. doi: 10.2147/ijn.s50061

Aninwene, George E., II, Stout, David, Yang, Zifan, & Webster, Thomas J. (2013). Nano-BaSO4:a novel antimicrobial additive to pellethane. International Journal of Nanomedicine, 8, 1197-1205. doi: 10.2147/ijn.s40300

Aninwene, George E., II, Webster, Thomas J., & Ieee. (2013). Nano-BaSO4: A Novel Bacteriostatic Polymer Additive. 2013 39th Annual Northeast Bioengineering Conference (Nebec 2013), 141-142. doi: 10.1109/nebec.2013.117

Crear, Jara, Kummer, Kim M., & Webster, Thomas J. (2013). Decreased cervical cancer cell adhesion on nanotubular titanium for the treatment of cervical cancer. International Journal of Nanomedicine, 8, 995-1001. doi: 10.2147/ijn.s38500

Durmus, Naside Gozde, Taylor, Erik N., Kummer, Kim M., & Webster, Thomas J. (2013). Enhanced Efficacy of Superparamagnetic Iron Oxide Nanoparticles Against Antibiotic-Resistant Biofilms in the Presence of Metabolites. Advanced Materials, 25(40), 5706-+. doi: 10.1002/adma.201302627

Durmus, Naside Gozde, & Webster, Thomas J. (2013). Eradicating Antibiotic-Resistant Biofilms with Silver-Conjugated Superparamagnetic Iron Oxide Nanoparticles. Advanced Healthcare Materials, 2(1), 165-171. doi: 10.1002/adhm.201200215

Dyondi, Deepti, Webster, Thomas J., & Banerjee, Rinti. (2013). A nanoparticulate injectable hydrogel as a tissue engineering scaffold for multiple growth factor delivery for bone regeneration. International Journal of Nanomedicine, 8, 47-59. doi: 10.2147/ijn.s37953

Ercan, Batur, Khang, Dongwoo, Carpenter, Joseph, & Webster, Thomas J. (2013). Using mathematical models to understand the effect of nanoscale roughness on protein adsorption for improving medical devices. International Journal of Nanomedicine, 8, 75-81. doi: 10.2147/ijn.s47286

Geilich, Benjamin M., & Webster, Thomas J. (2013). Reduced adhesion of Staphylococcus aureus to ZnO/PVC nanocomposites. International Journal of Nanomedicine, 8, 1177-1184. doi: 10.2147/ijn.s42010

Geilich, Benjamin M., & Webster, Thomas J. (2013). The First International Translational Nanomedicine Conference Boston, MA, USA, 26-28 July 2013. Nanomedicine, 8(11), 1747-1749. doi: 10.2217/nnm.13.162

Geilich, Benjamin M., Webster, Thomas J., & Ieee. (2013). Reduced Adhesion of Staphylococcus aureus to ZnO/PVC Nanocomposites. 2013 39th Annual Northeast Bioengineering Conference (Nebec 2013), 7-8. doi: 10.1109/nebec.2013.132

Hickey, Daniel J., Webster, Thomas J., & Ieee. (2013). Characterizing stem cell proliferation on magnesium nanoparticle mineralized poly(l-lactic acid) scaffolds for enthesis applications. 2013 39th Annual Northeast Bioengineering Conference (Nebec 2013), 117-118. doi: 10.1109/nebec.2013.65

Hoff, Dan, Sheikh, Lubna, Bhattacharya, Soumya, Nayar, Suprabha, & Webster, Thomas J. (2013). Comparison study of ferrofluid and powder iron oxide nanoparticle permeability across the blood-brain barrier. International Journal of Nanomedicine, 8, 703-710. doi: 10.2147/ijn.s35614

Jain, Shilpee, Webster, Thomas J., Sharma, Ashutosh, & Basu, Bikramjit. (2013). Intracellular reactive oxidative stress, cell proliferation and apoptosis of Schwann cells on carbon nanofibrous substrates. Biomaterials, 34(21), 4891-4901. doi: 10.1016/j.biomaterials.2013.03.055

Kalmodia, Sushma, Basu, Bikramjit, & Webster, Thomas J. (2013). Gene expression in osteoblast cells treated with submicron to nanometer hydroxyapatite-mullite eluate particles. Journal of Biomaterials Applications, 27(7), 891-908. doi: 10.1177/0885328211430422

Kumar, Alok, Webster, Thomas J., Biswas, Krishanu, & Basu, Bikramjit. (2013). Flow cytometry analysis of human fetal osteoblast fate processes on spark plasma sintered hydroxyapatite-titanium biocomposites. Journal of Biomedical Materials Research Part A, 101(10), 2925-2938. doi: 10.1002/jbm.a.34603

Kummer, Kim M., Taylor, Erik N., Durmas, Naside G., Tarquinio, Keiko M., Ercan, Batur, & Webster, Thomas J. (2013). Effects of different sterilization techniques and varying anodized TiO2 nanotube dimensions on bacteria growth. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 101B(5), 677-688. doi: 10.1002/jbm.b.32870

Leuba, Kohana D., Durmus, Naside Gozde, Taylor, Erik N., & Webster, Thomas J. (2013). Short communication: carboxylate functionalized superparamagnetic iron oxide nanoparticles (SPION) for the reduction of S. aureus growth post biofilm formation. International Journal of Nanomedicine, 8, 731-736. doi: 10.2147/ijn.s38256

Liu, Luting, Webster, Thomas J., & Ieee. (2013). Preparation of Nanotubular PDMS/PVC Molds for Reduced Catheter Inflammation and Infection. 2013 39th Annual Northeast Bioengineering Conference (Nebec 2013), 74-75. doi: 10.1109/nebec.2013.128

Liu, Xiong, & Webster, Thomas J. (2013). Nanoinformatics for biomedicine: emerging approaches and applications. International Journal of Nanomedicine, 8, 1-5. doi: 10.2147/ijn.s41253

Meng, Xiangling, Stout, David A., Sun, Linlin, Beingessner, Rachel L., Fenniri, Hicham, & Webster, Thomas J. (2013). Novel injectable biomimetic hydrogels with carbon nanofibers and self assembled rosette nanotubes for myocardial applications. Journal of Biomedical Materials Research Part A, 101(4), 1095-1102. doi: 10.1002/jbm.a.34400

Nhiem, Tran, & Webster, Thomas J. (2013). Understanding magnetic nanoparticle osteoblast receptor-mediated endocytosis using experiments and modeling. Nanotechnology, 24(18). doi: 10.1088/0957-4484/24/18/185102

Ross, Alexandra P., & Webster, Thomas J. (2013). Anodizing color coded anodized Ti6Al4V medical devices for increasing bone cell functions. International Journal of Nanomedicine, 8, 109-117. doi: 10.2147/ijn.s36203

Shi, Di, Hoff, Dan, Sheikh, Lubna, Bhattacharya, Soumya, Nayar, Suprabha, Webster, Thomas J., & Ieee. (2013). Using an in vitro Blood-Brain Barrier Model to Characterize Magnetic Nanoparticle Permeability. 2013 39th Annual Northeast Bioengineering Conference (Nebec 2013), 231-232. doi: 10.1109/nebec.2013.150

Stout, D. A., Durmus, N. G., & Webster, T. J. (2013). Synthesis of carbon based nanomaterials for tissue engineering applications. In A. K. Gaharwar, S. Sant, M. J. Hancock & S. A. Hacking (Eds.), Nanomaterials in Tissue Engineering: Fabrication and Applications (pp. 119-157).

Stout, D. A., Yoo, J., Santiago-Miranda, A. N., & Webster, T. J. (2013). Mechanisms of greater cardiomyocytes functions on conductive nanoengineered composites for cardiovascular applications (vol 7, 5653, 2012). International Journal of Nanomedicine, 8, 295-295. doi: 10.2147/ijn.s40500

Sun, Linlin, Webster, Thomas J., Hemraz, Usha D., Fenniri, Hicham, & Ieee. (2013). Enhanced Skin Cell Fuctions on Bioactive Rosette Nanotube Composites. 2013 39th Annual Northeast Bioengineering Conference (Nebec 2013), 35-36. doi: 10.1109/nebec.2013.91

Tran, Phong A., & Webster, Thomas J. (2013). Understanding the wetting properties of nanostructured selenium coatings: the role of nanostructured surface roughness and air-pocket formation. International Journal of Nanomedicine, 8, 2001-2009. doi: 10.2147/ijn.s42970

Tran, Phong A., & Webster, Thomas J. (2013). Antimicrobial selenium nanoparticle coatings on polymeric medical devices. Nanotechnology, 24(15). doi: 10.1088/0957-4484/24/15/155101

Wang, Qi, Perez, J. Manuel, & Webster, Thomas J. (2013). Inhibited growth of Pseudomonas aeruginosa by dextran- and polyacrylic acid-coated ceria nanoparticles. International Journal of Nanomedicine, 8, 3395-3399. doi: 10.2147/ijn.s50292

Wang, Qi, & Webster, Thomas J. (2013). Short communication: inhibiting biofilm formation on paper towels through the use of selenium nanoparticles coatings. International Journal of Nanomedicine, 8, 407-411. doi: 10.2147/ijn.s38777

Wang, Qi, & Webster, Thomas J. (2013). Nanostructured Selenium – A Novel Biologically-Inspired Material for Antibacterial Medical Device Applications. Biomimetics: Advancing Nanobiomaterials and Tissue Engineering, 203-220.

Wang, Qi, Webster, Thomas J., & Ieee. (2013). Bacteria Fighting Paper Towels: The Influence of Selenium Nanoparticles. 2013 39th Annual Northeast Bioengineering Conference (Nebec 2013), 31-32. doi: 10.1109/nebec.2013.55

Wang, Yongchen, Zhang, Lijuan, Sun, Linlin, & Webster, Thomas J. (2013). Increased healthy osteoblast to osteosarcoma density ratios on specific PLGA nanopatterns. International Journal of Nanomedicine, 8, 159-166. doi: 10.2147/ijn.s36408

Webster, Thomas J. (2013). Interview Nanomedicine: past, present and future. Nanomedicine, 8(4), 525-529. doi: 10.2217/nnm.13.37

Weng, Lucy, & Webster, Thomas J. (2013). Nanostructured magnesium has fewer detrimental effects on osteoblast function. International Journal of Nanomedicine, 8, 1773-1781. doi: 10.2147/ijn.s39031

Yao, Chang, Hedrick, Matt, Pareek, Gyan, Renzulli, Joseph, Haleblian, George, & Webster, Thomas J. (2013). Nanostructured polyurethane-poly-lactic-co-glycolic acid scaffolds increase bladder tissue regeneration: an in vivo study. International Journal of Nanomedicine, 8, 3285-3296. doi: 10.2147/ijn.s44901

Zhang, Lijuan, & Webster, Thomas J. (2013). Effects of chemically modified nanostructured PLGA on functioning of lung and breast cancer cells. International Journal of Nanomedicine, 8, 1907-1919. doi: 10.2147/ijn.s41570